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Assessment of the Bioaccessibility of Micronized Copper Wood on Simulated Stomach FluidSource

The widespread use of copper-treated lumber has increased the potential for human exposure. Moreover, there is a lack of information on the fate and behavior of copper-treated wood particles following oral ingestion. In this study, the in vitro bioaccessibility of copper from copper-treated wood dust in simulated stomach fluid and DI water was determined. Three copper-treated wood products, liquid alkali copper quaternary and two micronized copper quarternary from different manufacturers, were incubated in the extraction media then fractionated by centrifugation and filtration through 0.45 m and 10 kDa filters. The copper concentrations from isolated fractions were measured using Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Total amounts of copper from each wood product were also determined using microwave-assisted acid digestion of dried wood samples and quantification using ICP-OES. The percent in vitro bioaccessible copper was between 83 and 90 % for all treated wood types. However, the percent of copper released in DI water was between 14 and 25 % for all wood products. This data suggests that copper is highly bioaccessible at low pH and may pose a potential human exposure risk upon ingestion. This dataset is associated with the following publication: Santiago-Rodrigues, L., J.L. Griggs, K. Bradham , C. Nelson , T. Luxton , W. Platten , and K. Rogers. Assessment of the bioaccessibility of micronized copper wood in synthetic stomach fluid. Environmental Nanotechnology, Monitoring and Management. Elsevier B.V., Amsterdam, NETHERLANDS, 4: 85-92, (2015).

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Tags:
bioaccessibilitycopperhuman exposuremicronized coppersynthetic stomach fluidwood
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United State Environmental Protection Agencyabout 1 year ago
EPA - STORET Legacy Data CenterSource

EPA no longer updates this information, but it may be useful as a reference or resource. Welcome to the STORET Legacy Data Center, site of the world's largest repository of ambient Water Quality Data. From this site you will be able to access a database that holds over 200 million water sample observations from about 700,000 sampling sites for both surface and ground water.This web site allows both scientists and the general public to access the historical data from the legacy STORET system. First-time users should narrow their search based on the options from the Query page, while experienced users may jump to the no-frills Advanced Query form for requesting data. Legacy STORET contains data of undocumented quality. Further, the data in this system is static, and all new data are being entered into Modernized STORET. Background information about the Office of Water and the history of STORET may be found by following the Purpose link. For more information on the layout of this site, please follow the Site Map link. Internet Archive URL: https://web.archive.org/web/*/https://www3.epa.gov/storet/legacy/gateway.htm

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Other (Public Domain)
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AluminumEPAFlowSTORETambient water qualityarsenicbariumcadmiumcarbonchloridecoliformconductancecopperdepthdissolved oxygeneffluentfecal coliformhardnesshistorical water qualityironlakesmagnesiummanganesemonitoring stationsnitrogenpHphosphoruspower plantspublic waterriversseleniumsodiumstreamswells
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United States Environmental Protection Agencyabout 1 year ago