Formaldehyde air concentration data and decontamination efficacy data from controlled laboratory studies. This dataset is associated with the following publications: Choi, Y., M. Sunderman, M. McCauley, Z. Willenberg, J. Wood, S. Serre, L. Mickelsen, S. Willison, R. Rupert, J. Muniz-Ortiz, S. Casey, and W. Calfee. Formaldehyde Vapor Characteristics in Varied Decontamination Environments. Applied Biosafety. SAGE Publications, THOUSAND OAKS, CA, USA, 25(2): 24, (2020). Choi, Y., M. Sunderman, M. McCauley, W. Richter, Z. Willenberg, J. Wood, S. Serre, L. Mickelsen, S. Willison, R. Rupert, J. Muniz-Ortiz, S. Casey, and W. Calfee. Decontamination of Bacillus Spores with Formaldehyde Vapor under Varied Environmental Conditions. JOURNAL OF APPLIED MICROBIOLOGY. Blackwell Publishing, Malden, MA, USA, 25(2): 14, (2020).