Data from the Centers for Disease Control and Prevention on tuberculosis (TB) incidence in the United States from 1953 to 2015, including TB cases and case rates per 100,000 population. Case data after 1974 are not comparable to prior years due to changes in the surveillance case definition that became effective in 1975. The 1993–2015 TB case counts and rates were updated using the following sources: Bridged-Race 1990–1999 Intercensal Population Estimates for 1990–1999; Intercensal Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico: April 1, 2000 to July 1, 2010; and Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico: April 1, 2010 to July 1, 2015. __Connected to Sustainable Development Goal Indicator 3.3.2 - Tuberculosis incidence per 1,000 population__