data-from-net-release-and-uptake-of-xenometabolites-across-intestinal-hepatic-muscle-and-renal-

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Calculated net balances for LC/MS data from Mercer et al.

Organ Net Balance Data for Mercer et al.

LC/MS peak area data for xenometabolites in Mercer et al.

LC/MS data for Mercer et al.

Supplemental Figure 2 for Mercer et al manuscript: Absolute differences of xenometabolites from catheter ports in conscious overnight-fasted female pigs (n=12). Sampling sites included arterial, venous, renal, portal, and hepatic placed catheters.

Mercer et al Supplemental Figure 2

Supplemental Figure 1 for Mercer et al manuscript: Supplemental Figure 1: Inter-organ flux of all xenometablites in conscious overnight-fasted female pigs (n=12). A negative flux reflects net uptake (flux &lt; 0; indicated by bottom arrow) by the organ, whereas a positive flux reflects a net release (flux &gt; 0; indicated by top arrow) by the organ. Plasma flow measurements were determined with the para-aminohippuric acid dilution method, and were used along with metabolite concentrations to calculate flux (see Methods). R at top of arrow indicates ‘Release’, while U indicates ‘Uptake’.

Mercer et al Supplemental Figure 1

Mercer et al Supplemental Table 1: Raw differences of identified xenometabolites from port samples in conscious adult female pigs (n=10-12).

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