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HTTK: R Package for High-Throughput Toxicokinetics
OwnerUnited State Environmental Protection Agency - view all
Update frequencyunknown
Last updatedabout 1 year ago
Format
Overview

Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) . Chemical-specific in vitro data have been obtained from relatively high throughput experiments. Both physiologically-based ("PBTK") and empirical (e.g., one compartment) "TK" models can be parameterized for several hundred chemicals and multiple species. These models are solved efficiently, often using compiled (C-based) code. This dataset is associated with the following publication: Pearce , R., C. Strope , W. Setzer , N. Sipes , and J. Wambaugh. (Journal of Statistical Software) HTTK: R Package for High-Throughput Toxicokinetics. Journal of Statistical Software. American Statistical Association, Alexandria, VA, USA, 79(4): 1-26, (2017).

expocastexposurehigh-throughputhttkpharmacokineticstoxcast
Additional Information
KeyValue
dcat_modified2017-07-17
dcat_publisher_nameU.S. EPA Office of Research and Development (ORD)
guidhttps://doi.org/10.23719/1504255
ib1_trust_framework[]
language
Files
  • API
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