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Ozone-induced systemic and pulmonary effects are diminished in adrenalectomized rats
OwnerUnited State Environmental Protection Agency - view all
Update frequencyunknown
Last updatedabout 1 year ago
Format
Overview

This data set is an excel file pertaining to the study that examined ozone-induced systemic and pulmonary effects in rats that underwent SHAM surgery (control), adrenal demedullation or total bilateral adrenalectomy. Different pages of the spreadsheet shows individual animal data for markers of lung injury and inflammation, body weights, whole body plethysmography measurements, levels of circulating hormones and lipids, and circulating white blood cell count as well as platelet count. This dataset is associated with the following publication: Miller, D., S. Snow, M. Schladweiler , J. Richards , A. Ghio , A. Ledbetter , and U. Kodavanti. Acute Ozone-Induced Pulmonary and Systemic Metabolic Effects are Diminished in Adrenalectomized Rats#. TOXICOLOGICAL SCIENCES. Society of Toxicology, 150(2): 312-22, (2016).

adrenalectomyhpa-axislung injuryozonestress response
Additional Information
KeyValue
dcat_modified2016-08-22
dcat_publisher_nameU.S. EPA Office of Research and Development (ORD)
guidA-xsjt-216
ib1_trust_framework[]
language
Files
  • XLSX
    4863bd49-e95c-4326-b310-a24d4ac2d284
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ozone-induced-systemic-and-pulmonary-effects-are-diminished-in-adrenalectomized-rats
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