Triclosan Hershberger H295 data

OwnerUnited State Environmental Protection Agency - view all

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Last updatedabout 1 year ago

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Overview

Triclosan data from Hershberger experiment using castrated male rats. Data includes accessory sex tissue mean weights and thyroid gland weight following exposure to triclosan for 10 days both with and without testosterone stimulation. Also included are the thyroxine hormone means in these males. In addition, mean data on the in vitro adrenocortical cells for steroid hormone production (testosterone and estradiol) with a dose response of triclosan. This dataset is associated with the following publication: Farmer, W., G. Louis, A. Buckalew, D. Hallinger, and T. Stoker. Evaluation of Triclosan in the Hershberger and H295R Steroidogenesis Assays. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, USA, 194-199, (2018).

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dcat_modified2017-09-25

dcat_publisher_nameU.S. EPA Office of Research and Development (ORD)

guidhttps://doi.org/10.23719/1407648

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